Gold Nanoparticles for Pore Sizing - Nanopartz
Nanopartz has developed a perfect product for your pore sizing applications. The product is based on Spherical Gold Nanoparticles that are guaranteed in size and shape. This product will not aggregate nor ionically bind to the pore polymer. These Spherical Gold Nanoparticles are manufactured using proprietary methods that result in exact sizes, highly monodisperse sizes and shapes, long shelf lives, and with our proprietary polymer coating which imparts a slightly negative charge, is guaranteed to not aggregate nor bind to your pore polymer. Diameters from 1.8nm up to 1.5microns with size accuracies up to 0.1nm and size variances less than 2%. Every batch is completely characterized including size, monodispersity, aggregation, residual chemicals, and concentration. A Certificate of Analysis (COA) is provided for every order exhibiting TEM and UV-VIS images and data, as well as DLS data. Every product is in stock (99%) and is shipped same day.
Sizing Individual Au Nanoparticles in Solution with Sub-Nanometer Resolution, Sean R. German, Timothy S. Hurd, Henry S. White, and Tony L. Mega, ACS Nano 2015, 9, 7, 7186–7194 "We explored several nanoparticle manufacturers because we were unable to reproduce literature results for our application. One manufacturer recommended Nanopartz because of our desire for a narrow distribution of particle sizes. Nanopartz technical support helped us work through our application problems and suggested custom polymers that readily worked where others had failed. This really impressed us. They always provide quick delivery and helpful advice. We would highly recommend Nanopartz." Tony Mega, Revalesio Corporation |
Diameter (nm) |
Peak SPR Wavelength (nm) |
NPS/ml |
Molarity (pM) |
Moles |
Molar Ext. (M-1cm-1) |
Absorption Molar Ext. (M-1cm-1) |
Scattering Molar Ext. (M-1cm-1) |
Size Dispersity %PDI |
Size Accuracy (+/- nm) |
| 1.8 | n/a | 4.25E+16 | 7.10E+07 | 7.09E-08 | 7.05E+05 | 7.05E+05 | 0.00E+00 | <35% | 0.1 |
| 2.2 | n/a | 2.33E+16 | 3.90E+07 | 3.88E-08 | 1.29E+06 | 1.29E+06 | 0.00E+00 | <25% | 0.1 |
| 3 | n/a | 9.19E+15 | 1.50E+07 | 1.53E-08 | 3.26E+06 | 3.26E+06 | 0.00E+00 | <20% | 0.1 |
| 4 | n/a | 3.88E+15 | 6.50E+06 | 6.46E-09 | 7.74E+06 | 7.74E+06 | 0.00E+00 | <20% | 1 |
| 5 | 512 | 1.99E+15 | 3.30E+06 | 3.31E-09 | 1.51E+07 | 1.51E+07 | 0.00E+00 | <20% | 2 |
| 10 | 516 | 2.48E+14 | 4.10E+05 | 4.14E-10 | 1.21E+08 | 1.21E+08 | 0.00E+00 | <15% | 2 |
| 15 | 518 | 7.35E+13 | 1.20E+05 | 1.23E-10 | 4.08E+08 | 4.08E+08 | 0.00E+00 | <15% | 2 |
| 20 | 520 | 3.10E+13 | 5.20E+04 | 5.17E-11 | 9.67E+08 | 9.67E+08 | 0.00E+00 | <10% | 2 |
| 25 | 521 | 1.59E+13 | 2.60E+04 | 2.65E-11 | 1.89E+09 | 1.89E+09 | 0.00E+00 | <10% | 2 |
| 30 | 523 | 9.19E+12 | 1.50E+04 | 1.53E-11 | 3.26E+09 | 3.26E+09 | 0.00E+00 | <6% | 2 |
| 35 | 526 | 5.79E+12 | 9.60E+03 | 9.65E-12 | 5.18E+09 | 5.18E+09 | 0.00E+00 | <6% | 2 |
| 40 | 527 | 3.88E+12 | 6.50E+03 | 6.46E-12 | 7.74E+09 | 7.72E+09 | 2.24E+07 | <4% | 2 |
| 45 | 529 | 2.72E+12 | 4.50E+03 | 4.54E-12 | 1.10E+10 | 1.08E+10 | 2.03E+08 | <4% | 2 |
| 50 | 531 | 1.99E+12 | 3.30E+03 | 3.31E-12 | 1.51E+10 | 1.45E+10 | 5.88E+08 | <4% | 2 |
| 55 | 533 | 1.49E+12 | 2.50E+03 | 2.49E-12 | 2.01E+10 | 1.88E+10 | 1.30E+09 | <4% | 2 |
| 60 | 536 | 1.15E+12 | 1.90E+03 | 1.91E-12 | 2.61E+10 | 2.36E+10 | 2.48E+09 | <4% | 2 |
| 65 | 539 | 9.04E+11 | 1.50E+03 | 1.51E-12 | 3.32E+10 | 2.89E+10 | 4.33E+09 | <4% | 2 |
| 70 | 542 | 7.23E+11 | 1.20E+03 | 1.21E-12 | 4.15E+10 | 3.44E+10 | 7.09E+09 | <4% | 2 |
| 75 | 545 | 5.88E+11 | 9.80E+02 | 9.80E-13 | 5.10E+10 | 4.00E+10 | 1.10E+10 | <4% | 2 |
| 80 | 549 | 4.85E+11 | 8.10E+02 | 8.08E-13 | 6.19E+10 | 4.54E+10 | 1.65E+10 | <4% | 2 |
| 85 | 553 | 4.04E+11 | 6.70E+02 | 6.73E-13 | 7.42E+10 | 5.03E+10 | 2.39E+10 | <4% | 2 |
| 90 | 558 | 3.40E+11 | 5.70E+02 | 5.67E-13 | 8.81E+10 | 5.44E+10 | 3.37E+10 | <4% | 2 |
| 95 | 563 | 2.89E+11 | 4.80E+02 | 4.82E-13 | 1.04E+11 | 5.72E+10 | 4.65E+10 | <4% | 2 |
| 100 | 569 | 2.48E+11 | 4.10E+02 | 4.14E-13 | 1.21E+11 | 5.82E+10 | 6.27E+10 | <4% | 2 |
| 150 | 612 | 7.35E+10 | 1.20E+02 | 1.23E-13 | 4.08E+11 | 0.00E+00 | 4.08E+11 | <4% | 10 |
| 200 | n/a | 3.10E+10 | 5.20E+01 | 5.17E-14 | 9.67E+11 | 0.00E+00 | 9.67E+11 | <4% | 10 |
| 500 | n/a | 1.99E+09 | 3.30E+00 | 3.31E-15 | 1.51E+13 | 0.00E+00 | 1.51E+13 | <4% | 50 |
| 1000 | n/a | 2.48E+08 | 4.10E-01 | 4.14E-16 | 1.21E+14 | 0.00E+00 | 1.21E+14 | <4% | 100 |
| 1500 | n/a | 7.35E+07 | 1.20E-01 | 1.23E-16 | 4.08E+14 | 0.00E+00 | 4.08E+14 | <4% | 100 |
| Diameter includes polymer |
Optical Density >= 50, 5 for sizes >=500nm
|
Wt conc =2.5mg/mL
|
Wt % = 0.25%
|
| ppm = 2500 |
%PDI = Std Dev/Size
|
See Tech Note TN801 for definition of terms and method of analysis
|
All specs typical. May vary batch to batch. Exact values are measured for each batch
|
Shape monodispersity (% spheres) > 99.9%
|
Solution is 18MEG DI water
|
Residual Chemicals < 0.1%
|
Composition
These spherical gold nanoparticles are shipped in DI water with no measurable residual reactants. These particles encased in an impermeable polymer that is resistant to high levels of salt, variations in pH, aqueous and solvent solutions.
Custom Formulation
Diameters 1.8nm to 1500nm. Other sizes are special order. Please contact us.
Quantity
This product is available in 1mL volumes and larger. For orders larger than 1L, or for orders amounting over 10L per annum, please contact sales for quantity pricing.
Delivery
Standard sizes are in stock. Special order sizes are shipped in two weeks or less. All domestic shipments are sent Fed Ex Standard Overnight delivery, international Fed Ex Priority 2 day. No shipments on Fridays except for dried particles. Saturday shipping available for extra charge.
Shelf Life/Storage Temperature
This product is guaranteed for six months and should be stored at 4 °C after opening. Care must be taken to only use sterile glassware when working with this product.
Toxicity
This product is known to be noncytotoxic. This product has been sterilized and is biological free.
Sterilization
This product is sterilized.
Certifications
Every order comes with a Certification of Analysis that includes the following information. We use calibration traceable:
UV-VIS (Agilent 8453) for extinction and concentration measurements
NIR (Cary 500) for NIR extinction and concentration measurements
DLS (Malvern Nano ZS) for zeta potential measurement
ICP-MS (Varian 820-MS) for gold mass measurements
TEM (Phillips CM-100 100KV) for sizing
 vs. Diameter (nm).png)
How do you use these?
Dilute your product in DI water or another suitable buffer. Add to one side of your membrane. Use a UV VIS to measure the flow of any pore sizing gold nanoparticles as they flow through your membrane. UV VIS are typically sensitive to femtomolar concentrations.
Can I get these with a fluorophore on them?
You can, but you defeat the purpose of this product. First, fluorophore are very prone to ionically binding to pore membranes. Second, fluorimeters are not as sensitive as absorbance with gold nanoparticles, so your detection system is compromised.
How do you size your gold nanoparticles? Does the size include the capping agent?
We use three methods to specify our gold nanoparticles; TEM, UV VIS, and DLS. Each has its own advantages and disadvantages, and we use a weighted system to take advantage of each methods strengths. In the end, we place the strongest weight to the TEM method, particularly since we use samples sizes greater than 50 particles for each lot.
Do you really provide a TEM for my specific lot?
Yes, and not just for 5-10 particles, rather 50-100 are standard.
What is PDI?
PDI refers to polydispersity index and is equal to the standard deviation of the particle sizes divided by the average size.
"We explored several nanoparticle manufacturers because we were unable to reproduce literature results for our application. One manufacturer recommended Nanopartz because of our desire for a narrow distribution of particle sizes. Nanopartz technical support helped us work through our application problems and suggested custom polymers that readily worked where others had failed. This really impressed us. They always provide quick delivery and helpful advice. We would highly recommend Nanopartz."
Tony Mega, Revalesio Corporation
"In our multiphoton photoemission experiments, which are extra sensitive to any variations in nanoparticle geometry, we find Nanopartz rods and spheres to be consistently high quality. The photoemission distributions and other properties are representative of the fundamental particle shape, rather than defects, aggregates, or particle heterogeneity. The Nanopartz team is friendly, helpful, and knowledgeable - our go-to for publication-quality commercial nanoparticles."
Jacob Pettine, NSF Graduate Research Fellow
JILA, University of Colorado Boulder
Sizing Individual Au Nanoparticles in Solution with Sub-Nanometer Resolution, Sean R. German, Timothy S. Hurd, Henry S. White, and Tony L. Mega, ACS Nano 2015, 9, 7, 7186–7194
Determination of pore size distributions of virus filtration membranes using gold nanoparticles and their correlation with virus retention, P Kosiol, B Hansmann, M Ulbricht, V Thom - Journal of Membrane Science, 2017 - Elsevier
Example part number is PSZ11-10-DIH-2.5-1 where:
PSZ11 - Product family number for Pore Sizing Gold Nanoparticles
10 - Sphere diameter in nanometers. Other choices are 1.8 to 1500
DIH - Buffer, in this case 18MEG DI water. Other choices are PBS, MES, Sodium Borate, TRIS, contact us for solvents
2.5 - Amount, gold mg
1 - Volume, mL
Ordering by scrolling down and selecting the options from the selection below.