SHINERS SERS: Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy
SHINERS (Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy) is an advanced technique that uses core-shell nanoparticles to achieve high sensitivity in Raman spectroscopy. In SHINERS, gold nanoparticles (AuNPs) are coated with an ultrathin silica or alumina shell, which enhances Raman signals while preventing direct interaction between the nanoparticle and the target molecule. This technique has broad applications in chemical sensing, biosensing, surface science, and catalysis.
Nanopartz provides specialized gold nanoparticles for SHINERS applications, offering superior performance and reproducibility in molecular detection and characterization.
How SHINERS SERS Works
Mechanism of SHINERS SERS
-
Core-Shell Structure:
- A gold core provides the plasmonic enhancement.
- A thin silica shell isolates the gold core from the analyte, ensuring no chemical interference.
- Laser Interaction:
- A laser excites the plasmonic resonance in the gold nanoparticle.
- The shell allows the analyte molecules to be in close proximity but not adsorbed onto the core, enhancing the Raman signal.
- Enhanced Raman Scattering:
- The interaction of the laser with the gold nanoparticle boosts the Raman scattering signal by several orders of magnitude, enabling detection of trace amounts of molecules.
Applications of SHINERS SERS
1. Chemical Sensing
SHINERS SERS is used to detect pollutants, hazardous chemicals, and trace compounds with exceptional sensitivity.
2. Biosensing
- Detection of biomarkers for disease diagnosis.
- Monitoring of DNA, proteins, and pathogens.
3. Surface Science
SHINERS allows for the analysis of molecular layers on catalysts, semiconductors, and polymers without interfering with the surface properties.
4. Catalysis Studies
Provides real-time monitoring of catalytic reactions at the molecular level.
Why Nanopartz Gold Nanoparticles for SHINERS?
Key Benefits:
-
High Purity:
Nanopartz gold nanoparticles are produced with high purity and precision, ensuring consistent results in SHINERS applications. -
Controlled Shell Thickness:
The silica shell thickness can be precisely tuned to optimize Raman signal enhancement. -
Biocompatibility:
Non-toxic coatings allow for use in biological environments. -
Superior Stability:
Nanopartz nanoparticles remain stable over time, providing reliable results.
Product Specifications
- Core Material: Gold (Au)
- Shell Material: Silica (SiO₂)
Part # |
Diameter (nm) |
Peak SPR Wavelength (nm) |
NPS/ml |
Molarity (pM) |
Moles |
Molar Ext. (M-1cm-1) |
Absorption Molar Ext. (M-1cm-1) |
Scattering Molar Ext. (M-1cm-1) |
Size Dispersity %PDI |
Size Accuracy (+/- nm) |
A611-1.8 |
1.8 |
n/a |
4.25E+16 |
7.10E+07 |
7.09E-08 |
7.05E+05 |
7.05E+05 |
0.00E+00 |
<35% |
0.1 |
A611-2.2 |
2.2 |
n/a |
2.33E+16 |
3.90E+07 |
3.88E-08 |
1.29E+06 |
1.29E+06 |
0.00E+00 |
<25% |
0.1 |
A611-3 |
3 |
n/a |
9.19E+15 |
1.50E+07 |
1.53E-08 |
3.26E+06 |
3.26E+06 |
0.00E+00 |
<20% |
0.1 |
A611-4 |
4 |
n/a |
3.88E+15 |
6.50E+06 |
6.46E-09 |
7.74E+06 |
7.74E+06 |
0.00E+00 |
<20% |
1 |
A611-5 |
5 |
512 |
1.99E+15 |
3.30E+06 |
3.31E-09 |
1.51E+07 |
1.51E+07 |
0.00E+00 |
<20% |
2 |
A611-10 |
10 |
516 |
2.48E+14 |
4.10E+05 |
4.14E-10 |
1.21E+08 |
1.21E+08 |
0.00E+00 |
<15% |
2 |
A611-15 |
15 |
518 |
7.35E+13 |
1.20E+05 |
1.23E-10 |
4.08E+08 |
4.08E+08 |
0.00E+00 |
<15% |
2 |
A611-20 |
20 |
520 |
3.10E+13 |
5.20E+04 |
5.17E-11 |
9.67E+08 |
9.67E+08 |
0.00E+00 |
<10% |
2 |
A611-25 |
25 |
521 |
1.59E+13 |
2.60E+04 |
2.65E-11 |
1.89E+09 |
1.89E+09 |
0.00E+00 |
<10% |
2 |
A611-30 |
30 |
523 |
9.19E+12 |
1.50E+04 |
1.53E-11 |
3.26E+09 |
3.26E+09 |
0.00E+00 |
<6% |
2 |
A611-35 |
35 |
526 |
5.79E+12 |
9.60E+03 |
9.65E-12 |
5.18E+09 |
5.18E+09 |
0.00E+00 |
<6% |
2 |
A611-40 |
40 |
527 |
3.88E+12 |
6.50E+03 |
6.46E-12 |
7.74E+09 |
7.72E+09 |
2.24E+07 |
<4% |
2 |
A611-45 |
45 |
529 |
2.72E+12 |
4.50E+03 |
4.54E-12 |
1.10E+10 |
1.08E+10 |
2.03E+08 |
<4% |
2 |
A611-50 |
50 |
531 |
1.99E+12 |
3.30E+03 |
3.31E-12 |
1.51E+10 |
1.45E+10 |
5.88E+08 |
<4% |
2 |
A611-55 |
55 |
533 |
1.49E+12 |
2.50E+03 |
2.49E-12 |
2.01E+10 |
1.88E+10 |
1.30E+09 |
<4% |
2 |
A611-60 |
60 |
536 |
1.15E+12 |
1.90E+03 |
1.91E-12 |
2.61E+10 |
2.36E+10 |
2.48E+09 |
<4% |
2 |
A611-65 |
65 |
539 |
9.04E+11 |
1.50E+03 |
1.51E-12 |
3.32E+10 |
2.89E+10 |
4.33E+09 |
<4% |
2 |
A611-70 |
70 |
542 |
7.23E+11 |
1.20E+03 |
1.21E-12 |
4.15E+10 |
3.44E+10 |
7.09E+09 |
<4% |
2 |
A611-75 |
75 |
545 |
5.88E+11 |
9.80E+02 |
9.80E-13 |
5.10E+10 |
4.00E+10 |
1.10E+10 |
<4% |
2 |
A611-80 |
80 |
549 |
4.85E+11 |
8.10E+02 |
8.08E-13 |
6.19E+10 |
4.54E+10 |
1.65E+10 |
<4% |
2 |
A611-85 |
85 |
553 |
4.04E+11 |
6.70E+02 |
6.73E-13 |
7.42E+10 |
5.03E+10 |
2.39E+10 |
<4% |
2 |
A611-90 |
90 |
558 |
3.40E+11 |
5.70E+02 |
5.67E-13 |
8.81E+10 |
5.44E+10 |
3.37E+10 |
<4% |
2 |
A611-95 |
95 |
563 |
2.89E+11 |
4.80E+02 |
4.82E-13 |
1.04E+11 |
5.72E+10 |
4.65E+10 |
<4% |
2 |
A611-100 |
100 |
569 |
2.48E+11 |
4.10E+02 |
4.14E-13 |
1.21E+11 |
5.82E+10 |
6.27E+10 |
<4% |
2 |
A611-150 |
150 |
612 |
7.35E+10 |
1.20E+02 |
1.23E-13 |
4.08E+11 |
0.00E+00 |
4.08E+11 |
<4% |
10 |
A611-200 |
200 |
n/a |
3.10E+10 |
5.20E+01 |
5.17E-14 |
9.67E+11 |
0.00E+00 |
9.67E+11 |
<4% |
10 |
A611-500 |
500 |
n/a |
1.99E+09 |
3.30E+00 |
3.31E-15 |
1.51E+13 |
0.00E+00 |
1.51E+13 |
<4% |
50 |
A611-1000 |
1000 |
n/a |
2.48E+08 |
4.10E-01 |
4.14E-16 |
1.21E+14 |
0.00E+00 |
1.21E+14 |
<4% |
100 |
A611-1500 |
1500 |
n/a |
7.35E+07 |
1.20E-01 |
1.23E-16 |
4.08E+14 |
0.00E+00 |
4.08E+14 |
<4% |
100 |
Optical Density >= 50, 5 for sizes >=500nm
|
Wt conc = 2.5mg/mL, 1mL volume typical
|
Wt % = 0.25%
|
| ppm = 2500 |
%PDI = Std Dev/Size
|
See Tech Note TN801 for definition of terms and method of analysis
|
All specs typical. May vary batch to batch. Exact values are measured for each batch
|
Shape monodispersity (% spheres) > 99.9%
|
Solution default is 18MEG DI water
|
Residual Chemicals < 0.1%
|
Part # |
Diameter (nm) |
Length (nm) |
Peak SPR Wave (nm) |
Aspect Ratio |
OD SPR (AU) |
Peak LSPR Wave (nm) |
OD LSPR (AU) |
Nanorods /mL |
Wt. conc (ug/ml) |
Wt. % |
PPM |
Molarity (nM) |
Picomoles |
SPR Molar Ext. (M-1cm-1) |
LSPR Molar Ext. (M-1cm-1) |
Peak SPR (nm) |
SPR Linewidth 80% (nm) |
A612-5-808 |
5 |
21 |
808 |
4.2 |
50 |
510 |
10 |
2.39E+14 |
1750 |
0.18% |
1750 |
398.72 |
3.99E+02 |
1.25E+08 |
2.51E+07 |
794-829 |
100 |
A612-5-780 |
5 |
19 |
780 |
3.8 |
50 |
510 |
10 |
2.67E+14 |
1750 |
0.18% |
1750 |
444.72 |
4.45E+02 |
1.12E+08 |
2.25E+07 |
765-794 |
100 |
A612-5-700 |
5 |
15 |
700 |
3 |
50 |
510 |
10 |
3.47E+14 |
1750 |
0.18% |
1750 |
578.14 |
5.78E+02 |
8.65E+07 |
1.73E+07 |
675-725 |
100 |
A612-10-2100 |
10 |
175 |
2100 |
17.5 |
50 |
510 |
10 |
6.73E+12 |
1750 |
0.18% |
1750 |
11.21 |
1.12E+01 |
4.46E+09 |
8.92E+08 |
1900-2300 |
300 |
A612-10-1400 |
10 |
102 |
1400 |
10.2 |
50 |
510 |
10 |
1.17E+13 |
1750 |
0.18% |
1750 |
19.47 |
1.95E+01 |
2.57E+09 |
5.14E+08 |
1300-1500 |
150 |
A612-10-1200 |
10 |
81 |
1200 |
8.1 |
50 |
510 |
10 |
1.48E+13 |
1750 |
0.18% |
1750 |
24.67 |
2.47E+01 |
2.03E+09 |
4.05E+08 |
1132-1300 |
150 |
A612-10-1064 |
10 |
67 |
1064 |
6.7 |
50 |
510 |
10 |
1.81E+13 |
1750 |
0.18% |
1750 |
30.13 |
3.01E+01 |
1.66E+09 |
3.32E+08 |
1022-1132 |
150 |
A612-10-980 |
10 |
59 |
980 |
5.9 |
50 |
510 |
10 |
2.09E+13 |
1750 |
0.18% |
1750 |
34.91 |
3.49E+01 |
1.43E+09 |
2.86E+08 |
965-1022 |
150 |
A612-10-950 |
10 |
55 |
950 |
5.5 |
50 |
510 |
10 |
2.22E+13 |
1750 |
0.18% |
1750 |
37 |
3.70E+01 |
1.35E+09 |
2.70E+08 |
925-965 |
150 |
A612-10-900 |
10 |
50 |
900 |
5 |
50 |
510 |
10 |
2.47E+13 |
1750 |
0.18% |
1750 |
41.11 |
4.11E+01 |
1.22E+09 |
2.43E+08 |
875-925 |
150 |
A612-10-850 |
10 |
45 |
850 |
4.5 |
50 |
510 |
10 |
2.78E+13 |
1750 |
0.18% |
1750 |
46.25 |
4.63E+01 |
1.08E+09 |
2.16E+08 |
829-875 |
100 |
A612-10-808 |
10 |
41 |
808 |
4.1 |
50 |
510 |
10 |
3.10E+13 |
1750 |
0.18% |
1750 |
51.68 |
5.17E+01 |
9.68E+08 |
1.94E+08 |
794-829 |
75 |
A612-10-780 |
10 |
38 |
780 |
3.8 |
50 |
510 |
10 |
3.36E+13 |
1750 |
0.18% |
1750 |
56.06 |
5.61E+01 |
8.92E+08 |
1.78E+08 |
765-794 |
65 |
A612-10-750 |
10 |
35 |
750 |
3.5 |
50 |
510 |
10 |
3.70E+13 |
1750 |
0.18% |
1750 |
61.67 |
6.17E+01 |
8.11E+08 |
1.62E+08 |
725-765 |
50 |
A612-10-700 |
10 |
29 |
700 |
2.9 |
50 |
510 |
10 |
4.44E+13 |
1750 |
0.18% |
1750 |
74 |
7.40E+01 |
6.76E+08 |
1.35E+08 |
675-725 |
40 |
A612-10-650 |
10 |
24 |
650 |
2.4 |
50 |
510 |
10 |
5.55E+13 |
1750 |
0.18% |
1750 |
92.5 |
9.25E+01 |
5.41E+08 |
1.08E+08 |
625-675 |
40 |
A612-10-600 |
10 |
19 |
600 |
1.9 |
50 |
510 |
10 |
7.40E+13 |
1750 |
0.18% |
1750 |
123.34 |
1.23E+02 |
4.05E+08 |
8.11E+07 |
575-625 |
40 |
A612-25-1400 |
25 |
245 |
1400 |
9.8 |
50 |
514 |
15 |
1.12E+12 |
2500 |
0.25% |
2500 |
1.86 |
1.86E+00 |
2.69E+10 |
8.06E+09 |
1232-1500 |
150 |
A612-25-1064 |
25 |
137 |
1064 |
5.5 |
50 |
514 |
15 |
2.05E+12 |
2500 |
0.25% |
2500 |
3.42 |
3.42E+00 |
1.46E+10 |
4.38E+09 |
1022-1232 |
150 |
A612-25-980 |
25 |
119 |
980 |
4.8 |
50 |
514 |
15 |
2.39E+12 |
2500 |
0.25% |
2500 |
3.98 |
3.98E+00 |
1.26E+10 |
3.77E+09 |
965-1022 |
150 |
A612-25-950 |
25 |
102 |
950 |
4.1 |
50 |
514 |
15 |
2.82E+12 |
2500 |
0.25% |
2500 |
4.7 |
4.70E+00 |
1.06E+10 |
3.19E+09 |
925-965 |
150 |
A612-25-900 |
25 |
96 |
900 |
3.8 |
50 |
514 |
15 |
3.01E+12 |
2500 |
0.25% |
2500 |
5.02 |
5.02E+00 |
9.95E+09 |
2.99E+09 |
875-925 |
150 |
A612-25-850 |
25 |
93 |
850 |
3.7 |
50 |
514 |
15 |
3.12E+12 |
2500 |
0.25% |
2500 |
5.2 |
5.20E+00 |
9.61E+09 |
2.88E+09 |
829-875 |
150 |
A612-25-808 |
25 |
90 |
808 |
3.6 |
50 |
514 |
15 |
3.24E+12 |
2500 |
0.25% |
2500 |
5.39 |
5.39E+00 |
9.27E+09 |
2.78E+09 |
794-829 |
150 |
A612-25-780 |
25 |
87 |
780 |
3.5 |
50 |
514 |
15 |
3.36E+12 |
2500 |
0.25% |
2500 |
5.6 |
5.60E+00 |
8.93E+09 |
2.68E+09 |
765-794 |
150 |
A612-25-750 |
25 |
85 |
750 |
3.4 |
50 |
514 |
15 |
3.45E+12 |
2500 |
0.25% |
2500 |
5.75 |
5.75E+00 |
8.70E+09 |
2.61E+09 |
725-765 |
65 |
A612-25-700 |
25 |
75 |
700 |
3 |
50 |
514 |
15 |
3.96E+12 |
2500 |
0.25% |
2500 |
6.61 |
6.61E+00 |
7.57E+09 |
2.27E+09 |
675-725 |
60 |
A612-25-650 |
25 |
71 |
650 |
2.8 |
50 |
514 |
15 |
4.22E+12 |
2500 |
0.25% |
2500 |
7.03 |
7.03E+00 |
7.11E+09 |
2.13E+09 |
625-675 |
60 |
A612-25-600 |
25 |
57 |
600 |
2.3 |
50 |
514 |
15 |
5.43E+12 |
2500 |
0.25% |
2500 |
9.05 |
9.05E+00 |
5.52E+09 |
1.66E+09 |
575-625 |
60 |
A612-25-550 |
25 |
34 |
550 |
1.4 |
50 |
514 |
15 |
1.01E+13 |
2500 |
0.25% |
2500 |
16.91 |
1.69E+01 |
2.96E+09 |
8.87E+08 |
525-575 |
60 |
A612-40-1064 |
40 |
208 |
850 |
5.2 |
50 |
520 |
20 |
5.30E+11 |
2500 |
0.25% |
2500 |
0.88 |
8.84E-01 |
5.66E+10 |
2.26E+10 |
1022-1232 |
150 |
A612-40-980 |
40 |
180 |
850 |
4.5 |
50 |
520 |
20 |
6.19E+11 |
2500 |
0.25% |
2500 |
1.03 |
1.03E+00 |
4.84E+10 |
1.94E+10 |
875-1022 |
150 |
A612-40-850 |
40 |
148 |
850 |
3.7 |
50 |
520 |
20 |
7.67E+11 |
2500 |
0.25% |
2500 |
1.28 |
1.28E+00 |
3.91E+10 |
1.57E+10 |
829-875 |
150 |
A612-40-808 |
40 |
134 |
808 |
3.4 |
50 |
520 |
20 |
8.56E+11 |
2500 |
0.25% |
2500 |
1.43 |
1.43E+00 |
3.51E+10 |
1.40E+10 |
794-829 |
150 |
A612-40-780 |
40 |
124 |
780 |
3.1 |
50 |
520 |
20 |
9.33E+11 |
2500 |
0.25% |
2500 |
1.55 |
1.55E+00 |
3.22E+10 |
1.29E+10 |
765-794 |
150 |
A612-40-750 |
40 |
112 |
750 |
2.8 |
50 |
520 |
20 |
1.05E+12 |
2500 |
0.25% |
2500 |
1.74 |
1.74E+00 |
2.87E+10 |
1.15E+10 |
725-765 |
150 |
A612-40-700 |
40 |
92 |
700 |
2.3 |
50 |
520 |
20 |
1.31E+12 |
2500 |
0.25% |
2500 |
2.19 |
2.19E+00 |
2.29E+10 |
9.14E+09 |
675-725 |
60 |
A612-40-650 |
40 |
80 |
650 |
2 |
50 |
520 |
20 |
1.55E+12 |
2500 |
0.25% |
2500 |
2.58 |
2.58E+00 |
1.94E+10 |
7.75E+09 |
625-675 |
60 |
A612-40-600 |
40 |
68 |
600 |
1.7 |
50 |
520 |
20 |
1.89E+12 |
2500 |
0.25% |
2500 |
3.15 |
3.15E+00 |
1.59E+10 |
6.35E+09 |
575-625 |
60 |
A612-40-550 |
40 |
60 |
550 |
1.5 |
50 |
520 |
20 |
2.21E+12 |
2500 |
0.25% |
2500 |
3.69 |
3.69E+00 |
1.36E+10 |
5.42E+09 |
525-575 |
60 |
A612-50-1064 |
50 |
245 |
1064 |
4.9 |
50 |
530 |
25 |
2.89E+11 |
2500 |
0.25% |
2500 |
0.48 |
4.82E-01 |
1.04E+11 |
5.18E+10 |
980-1232 |
150 |
A612-50-808 |
50 |
145 |
808 |
2.9 |
50 |
530 |
25 |
5.15E+11 |
2500 |
0.25% |
2500 |
0.86 |
8.58E-01 |
5.83E+10 |
2.91E+10 |
750-850 |
150 |
A612-50-700 |
50 |
110 |
700 |
2.2 |
50 |
530 |
25 |
7.08E+11 |
2500 |
0.25% |
2500 |
1.18 |
1.18E+00 |
4.24E+10 |
2.12E+10 |
650-750 |
150 |
A612-50-600 |
50 |
100 |
600 |
2 |
50 |
530 |
25 |
7.93E+11 |
2500 |
0.25% |
2500 |
1.32 |
1.32E+00 |
3.78E+10 |
1.89E+10 |
550-650 |
150 |
A612-70-750 |
70 |
120 |
750 |
1.7 |
50 |
530 |
25 |
3.49E+11 |
2500 |
0.25% |
2500 |
0.58 |
5.81E-01 |
8.60E+10 |
4.30E+10 |
700-800 |
150 |
A612-70-650 |
70 |
105 |
650 |
1.5 |
50 |
530 |
25 |
4.13E+11 |
2500 |
0.25% |
2500 |
0.69 |
6.88E-01 |
7.27E+10 |
3.63E+10 |
600-700 |
150 |
A612-70-550 |
70 |
91 |
550 |
1.3 |
50 |
530 |
25 |
4.98E+11 |
2500 |
0.25% |
2500 |
0.83 |
8.30E-01 |
6.02E+10 |
3.01E+10 |
500-600 |
150 |
Optical Density >= 50, volume = 1mL
|
All specs typical. May vary batch to batch. Exact values are measured for each batch
|
Solution default is 18MEG DI water
|
Residual Chemicals < 0.1%
|
Part # |
Diameter (nm) |
Length (nm) |
Aspect Ratio |
Peak SPR Wave (nm) |
SPR OD (1cm) |
Microgold /mL |
moles |
Wt. conc (ug/ml) |
Wt. % |
PPM |
Molarity (pM) |
SPR Molar Ext. (M-1cm-1) |
A613-500 |
75 |
500 |
6.7 |
510 |
0.25 |
6.18E+09 |
1.03E-14 |
250 |
0.03% |
250 |
10.3 |
2.43E+07 |
A613-1000 |
100 |
1000 |
10 |
510 |
0.25 |
1.71E+09 |
2.85E-15 |
250 |
0.03% |
250 |
2.85 |
8.78E+07 |
SPR = Transverse SPR peak
|
Longitudinal has no SPR peak
|
Shape monodispersity (% rods) > 95%
|
Size variation +/-10% (both dimensions)
|
Part # |
Diameter (nm) |
Length (nm) |
Aspect Ratio |
Peak SPR Wave (nm) |
Nanowires Vol (nm3) |
Nanowires /mL |
Wt. conc (ug/ml) |
Wt. % |
PPM |
Molarity (pM) |
SPR Molar Ext. (M-1cm-1) |
A614-1000 |
75 |
1000 |
13 |
510 |
4.31E+06 |
3.01E+09 |
250 |
0.03% |
250 |
5.02 |
9.96E+06 |
A614-2000 |
75 |
2000 |
27 |
510 |
8.72E+06 |
1.49E+09 |
250 |
0.03% |
250 |
2.48 |
2.02E+07 |
A614-4000 |
75 |
4000 |
53 |
510 |
1.76E+07 |
7.39E+08 |
250 |
0.03% |
250 |
1.23 |
4.06E+07 |
A614-6000 |
75 |
6000 |
80 |
510 |
2.64E+07 |
4.91E+08 |
250 |
0.03% |
250 |
0.82 |
6.10E+07 |
A614-10000 |
75 |
10000 |
133 |
510 |
4.40E+07 |
2.94E+08 |
250 |
0.03% |
250 |
0.49 |
1.02E+08 |
A614-20000 |
100 |
20000 |
200 |
510 |
1.57E+08 |
8.27E+07 |
250 |
0.03% |
250 |
0.14 |
3.63E+08 |
A614-40000 |
140 |
40000 |
286 |
510 |
6.15E+08 |
2.11E+07 |
250 |
0.03% |
250 |
0.04 |
1.42E+09 |
SPR = Transverse SPR peak
|
Longitudinal has no SPR peak
|
Shape monodispersity (% rods) > 95%
|
Size variation +/-10% (both dimensions)
|
Shiners gold nanoparticles
Composition
These nanoparticles are shipped in 18MEG DI water (default solution) with no measurable residual reactants.
Custom Formulation
Please contact us.
Quantity
This product is available in 1mL volumes and larger. Please note that for the larger spheres and rods, depending on silica thickness we cannot guarantee a complete yield. Yields may be as low as 50% of spec.
Introductory Kits
Please contact us.
Delivery
Standard sizes are in stock. Special order sizes are shipped in two weeks or less. All domestic shipments are sent Fed Ex Standard Overnight delivery, international Fed Ex Priority 2 day. No shipments on Fridays except for dried particles. Saturday shipping available for extra charge.
Functionalization
This product comes with a number of different options are bare with the silica exposed. The product is stable with silica coating only.
Shelf Life/Storage Temperature
This product is guaranteed for six months and should be stored at 4 °C after opening. Care must be taken to only use sterile glassware when working with this product.
Toxicity
This product is known to be noncytotoxic. This product has been sterilized and is biological free.
Sterilization
This product is sterilized.
For post sterilization testing, please choose Sterilization Certification.
For endotoxin purification, choose Endotoxin Purified.
Certifications
Every order comes with a Certification of Analysis that includes the following information. We use calibration traceable:
UV-VIS (Agilent 8453) for extinction and concentration measurements
NIR (Cary 500) for NIR extinction and concentration measurements
DLS (Malvern Nano ZS) for zeta potential measurement
ICP-MS (Varian 820-MS) for gold mass measurements
TEM (Phillips CM-100 100KV) for sizing
How do I determine the concentration of the product?
Simply divide the number of nanoparticles (nps) found on the included COA by the amount of solution you add.
Why do you sell your rods as OD-mLs and what does this mean?
This is because unlike spherical gold nanoparticles, the conversion from OD to mg is not linear with nanorod diameter. Consequently, for the same OD, the weight of the nanorods increases with diameter. 50 OD-mLs means that if you resuspend the material in 1mL of solvent, you will have an absorption of OD50 through a 1mL optical path.
Can I resuspend in water?
Yes
Can I suspend in silicon oil?
No
What is the shelf life if I never open the package and keep refrigerated?
Many years.
Should I store in the refrigerator?
Yes.
How do you size your gold nanoparticles? Does the size include the capping agent?
We use three methods to specify our gold nanoparticles; TEM, UV VIS, and DLS. Each has its own advantages and disadvantages, and we use a weighted system to take advantage of each methods strengths. In the end, we place the strongest weight to the TEM method, particularly since we use samples sizes greater than 50 particles for each lot.
Do you really provide a TEM for my specific lot?
Yes, and not just for 5-10 particles, rather 50-100 are standard.
Why are your small gold nanoparticles colored? I have seen 2nm particles on other website that look as clear as water.
All gold nanoparticles absorb and/or scatter. If you can't see them, then they probably aren't there.
What is OD?
Optical Density (OD) is measured by UV-VIS. An Optical Density OD=1 corresponds to a transmission of 10% through a 1cm cuvette. Optical Density is a nice unit to use since Optical Densities correlate linearly to concentration. So an Optical Density of 1.2 is equal to 1.2 times the concentration of a gold nanoparticle solution that has an Optical Density of 1. We use OD and concentration interchangingly as it is easier to refer to a solution of OD=1 rather than 2.35e12 nanoparticles. For all spheres up to 200nm, OD=1 does refer to 0.05mg/mL.
What is PDI?
PDI refers to polydispersity index and is equal to the standard deviation of the particle sizes divided by the average size.
"We have looked at many different gold nanoparticles samples from Nanopartz including spheres, rods, and microrods using single particle spectroscopy techniques and are extremely happy with the quality of the samples and the service provided by Nanopartz."
Stephan Link, PhD
Assistant Professor of Chemistry
Rice University
Cunniff, C. Z., Specht, S. E., Love, A. M., and others. "Investigation of Supported Metal Oxide Species with Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy." The Journal of Physical Chemistry C, vol. 123, no. 45, 2019, pp. 27660–27670.
Zhang, X., Li, X., and Zhao, B. "Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy for Surface Analysis." Analytical Chemistry, vol. 88, no. 23, 2016, pp. 11864-11871.
Li, J., Zheng, H., and Fan, Q. "Plasmon-Enhanced Raman Spectroscopy with Gold Nanoparticles for Molecular Diagnostics." Biosensors and Bioelectronics, vol. 92, 2017, pp. 425-431.
Gao, Y., et al. "Nanopartz Gold Nanoparticles for High-Resolution SHINERS Analysis of Catalytic Surfaces." Journal of Physical Chemistry C, vol. 123, no. 5, 2019, pp. 3021-3028.
The manufacturing method for these nanoparticles and the ability to measure the silica thicknesses are based on our proprietary method.
| Silica Coated Gold Nanoparticles | |
| Stability (salt,pH,chemicals) | High |
| Monovalent | No |
| Nonspecific binding | Very low |
| Sterilization | Yes |
- Covalent bonds insure specificity, stability, long shelf life
- Buffer Stability - stable from pH 4-9
- No sodium azide
- No BSA
- Polymer coating insures no aggregation in high salts, reduced nonspecific binding
- Stable
- Well Characterized
- Customer can select buffer
- Customer can select gold nanoparticle type, size and/or SPR
- Loading of all ligands is optimized
Example part number is PSH611-10-DIH-50-1-CS-EP where:
PSH11 - Product family number for Silica Coated Spherical Gold Nanoparticles. For Gold Nanorods, its A612 and so forth.
10 - Sphere diameter in nanometers. Other choices are 1.8 to 1500
3 - Silica Thickness
DIH - Buffer, in this case 18MEG DI water. Other choices are PBS, MES, Sodium Borate, TRIS
50 - Optical Density, in this case OD=50, optional 250
1 - Volume (mL). Other choices are 5mL, 10mL and more.
CS - Certified Sterilized - Though the product come sterilized, this option includes testing and certification.
EP - Endotoxin Purified - The product is endotoxin purified and certified.
Ordering by scrolling down and selecting the options from the selection below.